Hypercholesterolemia characterized by increased serum levels of total cholesterol, low-density lipoprotein cholesterol (LDL-C), non-high-density lipoprotein cholesterol (non-HDL‑C), and apolipoprotein B (apo B). And these are associated with increased risk of cardiovascular disease (CVD) and mortality. cholesterol is causal in development of atherosclerotic cardiovascular disease (ASCVD) & lowering cholesterol is associated with lower CV events. CVD in secondary […]
Information: Procalcitonin, a peptide precursor of calcitonin, a hormone synthesized by parafollicular C cells of thyroid gland, after exposure to bacterial toxins. Serum procalcitonin level increases 2-4 hours after bacterial infection. Procalcitonin can be detectable for up to 7 days. Patients ICU & sepsis- high procalcitonin have high risk of severe sepsis, septic shock, poor
HIRSUTISM Hirsutism- cosmetically unacceptable terminal hair growth in women, in a male pattern. (Or excessive terminal hair growth in women). Virilization- male physical characteristics development in women, like pronounced muscle development, deepening voice, clitoromegaly, male pattern baldness, & severe hirsutism. Causes: polycystic ovary syndrome, ovarian hyperthecosis, neoplastic disorders, steroidogenic enzyme defects, rarely medications, acromegaly, or
